porin

Conclusion A plasmid recombinant encoding porin B of Neisseria gonorrhoeae has been successfully constructed and expressed in E. coli.

结论淋病奈瑟菌孔蛋白PⅠB原核表达质粒构建正确。

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The deeper studies on the function of Porin would be of great importance in illuminating the mechanism of gonococcal pathogenesis and host anti-infection immunity.

深入研究孔蛋白的免疫功能，对阐明淋球菌的致病机制及宿主抗感染免疫机制具有重要意义。

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Objective: To construct an eukaryotic expression system carrying the Neisseria gonorrhoeae Porin IA ( PIA) gene.

目的：构建淋病奈瑟菌孔蛋白PIA（Porin IA）基因的真核表达系统，为淋病DNA疫苗的研究提供材料。

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Results from the mutational analysis and qRT-PCR suggested that the EnvZ/ OmpR system contributed to osmotic stress response of S. oneidensis and very likely engaged a similar strategy employed by E. coli, which involved reciprocal regulation of two porin coding genes.

突变分析和qRT-PCR结果表明，EnvZ/OmpR系统参与了S.oneidensis对渗透胁迫的反应，并很可能利用了与E.coli类似的策略，即对两个孔蛋白编码基因的表达进行反向调节。

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Intractable Constipation: Clinical Diagnosis, Treatment and Study of Aquaporin Gene Expression

顽固性便秘的临床诊治与aquaporins基因表达研究

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Porin A-specific antibody avidity in patients who are convalescing from meningococcal B disease

B型脑脊髓膜炎患者恢复过程中的孔蛋白A特异性抗体亲和力

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Construction and Sequence Analysis of A Recombinant Plasmid Harbouring the Porin Gene PIA of Neisseria gonorrhoeae

淋球菌主要外膜蛋白PIA原核重组质粒的构建及序列分析

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Renal aquaporin 2 water channel expression in congestive heart failure rat

充血性心力衰竭大鼠肾脏Aquaporin2水通道蛋白基因的表达

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Objective Clone the genes of porin PIB and PIA of Gonococcus. To construct a recombinant eukaryotic expression vector containing both porin gene PIB and PIA, and to confirm the expression of pCI-PIB-PIA in muscule cells.

目的克隆淋球菌孔蛋白PIB和PIA基因并构建融合蛋白真核表达质粒pCI-PIB-PIA，了解pCI-PIB-PIA能否被小鼠骨骼肌细胞摄取并表达。

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DTH was observed on the femoral leg of the rabbit administered intradermally with porin B.Slide agglutination reaction and bactericidal activity were measured by immunized rabbit serum in vitro.

后腿皮内注射孔蛋白B，观察迟发型超敏反应（DTH）、免疫血清体外玻片凝集及抗菌作用。

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Mycosporine-like amino acids ( MAAs ) strongly absorb UVR and protect cells against harmful UVR.

类菌孢素氨基酸(mycosporine-like aminoacids,间称MAAs ) 存在于许多生物体内,对紫外辐射 ( UVR) 有较高的吸收能力,被认为有保护细胞、减少UVR损伤的功能.

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Since the Hp adhesin conservative region ( AB) is outer membrane protein and porin type component, while these two kinds of protein are the excellent immunogen candidates of vaccination.

鉴于Hp已证实的四种粘附素保守区（AB）是外膜蛋白（OMP）和膜孔素（porin）样成分，而外膜蛋白和膜孔素样成分是优秀的疫苗候选抗原。

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The water permeability of biological membranes has been a longstanding problem in physiology, but the proteins responsible for this remained unknown until discovery of the Aquaporin 1 ( AQP1) water channel protein. Peter Agre was awarded the 2003 Nobel Prize in Chemistry for this discovery.

水通道蛋白（Aquaporin，AQP）的发现解决了生理学上一个长期存在的关于生物膜水通透性的问题，Peter Agre因此获得2003年诺贝尔奖。

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Immune response induced with the vaccine of porin of gonorrhoeae in animals

淋球菌孔蛋白疫苗在动物体内诱导的免疫应答

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The expression of porin protein were detected by SDS-PAGE.

利用SDS-PAGE测定淋球菌外膜孔蛋白的表达；

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Objective To clone porin B ( P ⅰ B) sequences of Neisseria gonorrhoeae and analyze the protein expression as basis of research in detection, prophylactic and therapeutic vaccine against the pathogen infection.

目的克隆和分析淋病奈瑟菌孔蛋白（porinⅠB，PⅠB）的基因序列并表达相应的蛋白质，为淋病奈瑟菌感染的检测和基因工程疫苗的研究与开发建立基础。

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Results: There were 35 cases of type-A porin genotype and 46 cases of type B within the 71 cases.

结果：孔蛋白基因型为A型的有35例，其余46例为B型。

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Study on Level of Delayed-type Hypersensitivity ( DTH) and Transfered Protective rate of Immunized T Cell Induced by Porin of Salmonella Typhimurium in BALB/ C Mice

鼠伤寒沙门氏菌porin诱导BALB/C小鼠迟发性变态反应和T淋巴细胞转移保护的研究

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Porin is a transmembrane protein found in the outer membrane of mitochondria as well as in the outer membrane of gram positive bacteria.

孔蛋白是一种跨膜蛋白，主要存在于细菌质膜的外膜、线粒体和叶绿体的外膜上。

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Construction of Neisseria gonorrhoeae Porin B Plasmid Recombinant and Its Expression in E.coli and Identification of Fusion Protein

淋病奈瑟菌孔蛋白B原核重组质粒的构建、表达与蛋白鉴定

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The protective rate of porin to the mice challenged with 500 LD50 murine Salmonella typhi was 70%. The results showed good immunogenicity of STM-porin.

以500LD50鼠伤寒沙门氏菌攻击，其保护率为70%，提示STM－porin具有较强的免疫原性。

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Methods: Porin B of gonorrhoeae expressed in E. coli by a recombinant plasmid and purified, were administered subcutaneously into the rabbit back. The serum antibody change and the highest titer of the rabbit was dynamically examined after immunized by ELISA.

方法：兔背皮下注射经原核构建表达并纯化的淋球菌孔蛋白B，ELISA动态检测免疫后大耳兔血清抗体滴度的变化及最高效价；

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This article also gives a presumption to T-DNA's transport: The plant cell wall's porin may be T-DNA's natural channel.

对延宕至今的T DNA穿壁问题作了推测：植物细胞壁表面可能存有T DNA的天然穿壁孔道。

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Research of Multiple-antibiotic-resistance Negative Regulation Gene and Porin of Escherichia Coli

大肠杆菌多重耐药负性调节基因及膜孔蛋白的研究

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Using carbapenem antibiotic can induce the deletion of out membrance porin gene, thus increasing MIC values of carbapenem antibiotic.

碳青霉烯类药物的使用可以诱导外膜孔道蛋白基因缺失，从而增加对碳青霉烯类抗菌药物的MIC值。

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Expression of efflux pump protein and porin protein in multi-drug resistant strains of Neisseria gonorrhoeae

多重耐药淋病流行株孔蛋白和泵蛋白的表达

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Porin plays an important role in Neisseria gonorrhoeae survival and pathogenesis.

淋球菌孔蛋白对淋球菌的存活和致病起着重要作用.

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